Alternative Methodologies Used in Animal Research

If potentially painful / distressful procedures are proposed on the protocol form, the PI is required to document that there are no less painful / distressful procedures to accomplish the goals of the project.  Further, if there are less painful / distressful procedures to accomplish the aims of the project, the PI must provide a scientific  justification for not using the less painful approach.   The documentation process can be reasonably accomplished with a literature search that includes at least one of the "Alternatives" database.  Please use the resources below to help with your searches.

 Altweb 

 AVAR 

 AWIC 

 CAAT 

 FRAME 

 HSUS 

 ICCVAM 

 Nor. Red.
Centre
 

 NORINA 

Skin  Irritation 

 UCCAA 

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Additional Sites

Educational Use of Animal-Based Labs

The Use of Animals in Higher Education: Problems, Alternatives, and Recommendations

Animal Use Alternatives Thesaurus

The Netherlands Center for Alternatives to Animal Use

Training Models for Animal Procedures (models of animal anatomy for developing skills, procedures, and surgical methods)

Microsurgical Developments Foundation (rat model for use in teaching microsurgical techniques)

Tissuee Transformation Technologies (provider of cells from human tissues)

The Third R - Refinement

List of Virtual Dissection Websites

Antibody Resource Page

Humane Endpoints In Animal Experiments For Biomedical Research

InVitro Testing Industrial Platform

Skinthetic Laboratories